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3 Nicotine pharmacology and cardiovascular effects 3.1 Mechanisms of nicotine action As detailed by Benowitz (22) in his comprehensive review of nicotine pharmacology, nicotines addictive potential stems from its complex interaction with the nervous system, involving rapid central nervous system penetration and subsequent activation of neural reward pathways

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Both companies also express interest in developing new types of nicotine products, such as products which atomize nicotine instead of burning tobacco what has come to be known as the electronic cigarette.