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The observation that in our cohort only ~ 79% of patients and ~ 82% of probands fulfilled the currently defined minimal criteria for a suspicion of the disease, which require the presence of the combined major criterion 1, indicates that their strict application could lead to a lack of diagnoses

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For the tobacco industry, the larval feeding on tobacco (especially flue-cured and oriental) is the most significant damage

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From 2014 to 2015, the annual direct (medical) plus indirect costs of stroke in the United States was estimated to be $45.5 billion (Benjamin et al