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Ethionamide requires activation by the mycobacterial enzyme flavin monooxygenase (EthA) and the transcriptional repressor EthR to form ethionamide sulfoxide, which binds to NAD + and inhibits the enoyl-acyl carrier protein reductase (InhA), thereby blocking mycolic acid synthesis, responsible for cell death (Dover et al., 2007)

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It is crucial to avoid intimate contact with someone who has visible sores

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Understanding Nicotine Addiction Dependence on cigarettes is a twofold problem: the physical side of addiction to nicotine and the psychological side

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