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In fact, a 2018 study, based on data from the NYTS and other surveys, found that the decline in smoking among teenagers and young adults accelerated as vaping became increasingly common

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In light of its superior safety profile, Health Canada mandated a label change in 2013 advising thorough consideration of NRT before prescribing either varenicline or bupropion to any smoker, further stating that in many cases, nicotine replacement therapy should be tried before prescribing varenicline or bupropion [9], emphasizing the need to optimize the effectiveness of this first-line medication