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Tobacco is a labor-intensive crop, and even with the use of labor-saving technologies for some production, flue-cured tobacco requires approximately 100 hours of labor per acre, and burley tobacco requires 150 to 200 hours of labor per acre.[19] The tobacco season generally begins in February or March with cultivation of tobacco seedlings in greenhouses or plant beds

These labels are so problematic that the Food and Drug Administration has required Santa Fe Natural Tobacco Company, the maker of Natural American Spirit cigarettes, to remove the terms natural and additive-free from its product labels, advertising and promotional materials because they constitute reduced harm claims, which are banned without agency approval

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Alcohol during pregnancy