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glp-1 agonist gastric emptying dSummary of the interdependent relationships of emptying, GLP-1 receptor agonists and delayed
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NEJM Evidence

14 A 2017 meta-analysis of 52 randomized, controlled trials that evaluated DPP-4 inhibitors' effects on beta-cell function found that, in monotherapy studies, all agents except linagliptin resulted in improvements in cell function

Brainstem preproglucagon expressing fibers project to many areas of the brain with the most abundant projections to areas hypothalamic areas that control energy homeostasis including the arcuate nucleus (ARC), paraventricular nucleus (PVN), and dorsomedial nucleus (DMH) (Jin et al., 1988)

111,112 Autonomic neuropathy, resulting from hyperglycaemia-induced damage to the enteric nervous system that governs the internal and external anal sphincters, is the primary attributable factor
Diabetes 58, 22582266

Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with type 2 diabetes
