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Although delivery of nicotine to the brain is rapid, there is nevertheless significant pulmonary uptake and some delayed release of nicotine as evidenced by pulmonary positron emission tomography data and the slow decrease in arterial concentrations of nicotine between puffs

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Siegler V, Al-Hamad A, Johnson B, Wells C

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These findings highlight the importance of comprehensive, system-wide approaches that offer cessation support to all cancer survivors while also addressing strategies to increase readiness to quit