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The Centers for Disease Control and Prevention says nicotine is a highly addictive substance found in tobacco products, such as cigarettes, and nicotine replacement therapies, like nicotine gum

(Tobacco enthusiasts generally deride additive-filled, mass-produced cigarettes

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At nearly 2,700 pages, the TPP may be the longest, most complex, and exception-filled trade agreement ever negotiated

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In the meantime, given the agency's failure to rule on a single one of the 3,500 applications it has received so far, the case is weak for expanding its authority to even more dynamic sectors of the market.