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For example, a study conducted by the Research Institute on Addictions found that among individuals who were chronic partner abusers, the use of alcohol was associated with significant increases in the daily likelihood of male-to-female physical aggression, but the use of marijuana was not

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The Centers for Disease Control and Prevention state that the long-term effects of nicotine use are often caused by nicotine dependence, leading to withdrawal

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Studies have shown that histone modification is involved in the regulation of gene expression at the epigenetic level and plays an important role in the development, ageing, differentiation, apoptosis, and tumour migration of tissues, organs and cells [57,58,59,60,61,62]