ingredients of e cigarettes E-Cigarettes and Vaping Composition of electronic cigarette aerosol

But that isnt the reason you should be worried by nitrogen oxide, you should be worried as it is one the main chemicals (other than the nicotine) that gets you addicted to cigarettes

Smokers also show deeper lines around the mouth and in between the eyebrows

When they compared the relative risk between the groups, this study showed a risk 14% higher for smokers having chronic or recurrent rhinosinusitis, especially those who smoked more than 10 cigarettes per day

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This effect may be explained by the psychoactive effects of cannabis it stimulates our nervous system, thus increasing the heart rate, oxygen consumption, and eventually the blood pressure

Source: Goodnet.org