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Bauer, C

Prolonged use of snus, especially close to bedtime, may exacerbate sleep-related problems

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Bupropion SR (Zyban): Originally used as an antidepressant, Bupropion has been found to help with smoking cessation by influencing neurotransmitters associated with nicotine addiction

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Reported prevalence rates from these studies range from 8.2-47%, so further research is necessary to be able to definitively state the prevalence of GTS