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Also, nicotine seems to up-regulate the neuropeptide Y (NPY) and orexins, molecules for feeding, while down-regulate their receptors [249]

For example, the Surgeon Generals report details how low-tar cigarettes, advertised by tobacco companies as safer, were later found to be just as harmful

However, it doesnt just cause you to feel high. When THC attaches to cannabinoid receptors in the eyes, they dilate (or widen) the blood vessels and capillaries

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doi: 10.1172/jci.insight.94040, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 35.Berkowitz L, Pardo-Roa C, Salazar GA, Salazar-Echegarai F, Miranda JP, Ramrez G, et al

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