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I guess I just get frustrated because I spent two tours in Viet Nam and wrecked my knees climbing out on ropes in the ship yards to take down the radio antennas, but did not have major knee problems until I was out two months

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doi: 10.1093/oxfordjournals.aje.a008887

It affects the sympathetic nervous system, often known as the bodys fight or flight response and causes the release of stress hormones such as adrenaline and noradrenaline

Nicotine increases the expression of kidney injury molecule-1, the classic epithelial-mesenchymal transition (EMT) markers, vimentin, fibronectin, and production of -smooth muscle actin (-SMA), TGF-, MCP-1, and ROS in the renal epithelium