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Exposure to e-cigarette aerosol extracts increases the dose of cisplatin required to induce a 50% reduction in cell growth (IC50) The determination of the concentrations of a drug needed to induce a 50% reduction in cell growth (the half-maximal inhibitory concentration or IC50) is an in vitro measure essential for understanding the pharmacological potency of a drug under specific conditions 37 , and has been reported to be predictive of cancer chemoresistance in patients 38

Since then, there has been an explosion of popularity surrounding these devices with millions worldwide switching over from traditional cigarettes to vaping