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Datura stramonium , or thorn-apple, already had a following in the US, but its British popularity began as an alternative to similar treatments learnt from Indian medicine during the East India Companys control over the subcontinent

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Preparing to Quit: Setting a Quit Date and Plan The first step to achieving a goal is deciding to do it - and the next step is making a plan to succeed

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The protagonist is recovering from bubonic plague, local medicine is around the Dark Age level, opium is realistically the most practical painkiller available in the world, and once he's coherent enough to realize what he's been given he immediately checks with an expert on the issue of addiction