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Over time, this material calcifies into small stones, which can cause further irritation and infection

This fermentation process changes the flavour profile of the tobacco as there is less oxygen touching all parts of the tobacco because the flake slices are a part of a larger block of compressed tobacco

A clinical study found that tobacco-free individuals exposed to secondhand e-cigarette aerosols for 30 min reported respiratory and ocular symptoms and that throat irritation persisted beyond the exposure window (161)

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The health warning will read: "Warning: the Surgeon General has determined that cigarette smoking is dangerous to your health." In a concession to cigarette makers, however, the bill bars the Federal Trade Commission from requiring the warning to be included in all printed advertising until July 1971