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Description
Case reports of possible neuropsychiatric effects of varenicline, including depression, psychosis, and suicide, were received by the FDA soon after varenicline entered the market in 2006 (61)
Accessed May 3, 2024

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A: Nicotine pouches still pose health risks due to nicotines addictive nature and its effects on blood pressure and oral health

To relax the log(linear) assumption usually applied to continuous doseresponse risk and make the estimates robust to the placement of spline knots, we used an ensemble spline approach to fit the functional form of the doseresponse relationship

He still is, he just doesnt sound like it
