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Macrophage Polarization GLP-1 agonists promote macrophages to change their inflammatory status from pro-inflammatory (M1) to anti-inflammatory (M2), which reduces inflammation in both the blood vessels and heart [43]

Diabetologia 68 , 16801695 (2025)

For high-risk patients or those with documented decline despite optimal lifestyle measures, referral to clinical trials of emerging anabolic/anti-catabolic therapies is appropriate

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Conversely, abnormal blood glucose levels have been shown to elevate cancer risk and decrease survival rates in cancer patients [12, 50]

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