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The cough prevalence, which encompassed 13 studies 21,31,40,42-45,48,50,52,53,61,65 and a total of 17236 transitioning e-cigarette users, utilized a random-effects model to determine a pooled cough prevalence of 18% (95% CI: 0.140.23)

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Previous studies suggested significant ethnic differences in the metabolism of CLO between Caucasians and Asians and that the induction effect of PAHs on CYP1A2 enzyme activity in Asians is weaker than that in Caucasians (24, 25)

Long-term upregulation of protein kinase A and adenylate cyclase levels in human smokers

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