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Tobacco smoking is also a major risk factor for cardiovascular disease and chronic obstructive pulmonary disease (COPD)

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Toxicol Sci 132:253267 Lindner K, Strbele M, Schlick S, Webering S, Jenckel A, Kopf J, Danov O, Sewald K, Buj C, Creutzenberg O, Tillmann T, Pohlmann G, Ernst H, Ziemann C, Httmann G, Heine H, Bockhorn H, Hansen T, Knig P, Fehrenbach H (2018) Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons