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alternatively, smoking cessation may also lead to changes that favor the develop- ment of insulin resistance, depending on the resulting variations in body weight [75]

The mechanism by which cigarette (tobacco) smoke causes adverse health outcomes involves multiple complex steps resulting from the exposure to free radicals from the components of tobacco smoke, leading to increased oxidative stress, inflammation, and DNA damage [9]

Other harmful constituents of tobacco smoke include polycyclic aromatic hydrocarbons (PAHs), although their role in pancreatic disease remains unclear (7, 36)

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While Simon Bolivar is officially memorialized by the state in bronze or stone depending on the monument, its the rebellious icon of Ches image that the people seem to have adopted, especially in the city of El Triunfo