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Therefore, this manuscript aims to comprehensively review the currently available literature regarding the use of the new incretin analogs semaglutide and tirzepatide in patients with T1D (at different stages of the disease) and LADA, examining the safety and efficacy of these medications administered for different purposes in real-world settings
In TRIUMPH-1 the pivotal Phase 3 obesity trial, reported May 21, 2026 participants on the 12 mg dose lost an average of 28.3% of their body weight (70.3 lbs) at 80 weeks , versus 2.2% on placebo

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doi: 10.1038/nbt0898-728

Our biology, which once served us well in a feast-or-famine setting, now makes us vulnerable to an environment abundant in calorie-dense foods
