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The concept is a bit obtuse and certainly sounds more than a little old-fashioned when viewed from a modern perspective

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The analysis found that when compared to peers who had never smoked: Smokers who quit between ages 15 to 34 had about the same risk of dying from heart disease or stroke

Graham In JAMA (Journal of the American Medical Association) 1950 (volume 143), pages 329-336 Reprinted with commentary in The Journal of NIH Research May 1982 [Curators note: One of the individuals who played a major role in proving a causal association between cigarette smoking and lung cancer was a medical student, Ernst Wynder

As established scientific principles falter, their intertwined personal and professional journeys unfold against the backdrop of an emerging global existential threat