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In addition to the airways, vagus nerves innervate several organs in the body, including the oesophagus, heart and gastrointestinal tract (Berthoud & Neuhuber, 2000)

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However, reflux monitoring off therapy should not be performed alone as a diagnostic test for GERD in those with endoscopic evidence of Los Angeles (LA) grade C or D reflux esophagitis or in patients with long-segment Barretts esophagus