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What the published research reported A phase-2 randomized trial published in the New England Journal of Medicine in 2023 studied retatrutide in adults with obesity and reported substantial, dose-dependent reductions in body weight over 48 weeks, alongside a gastrointestinal side-effect profile broadly similar to other incretin drugs

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Hypothyroidism: hypothyroidism is a condition in which thyroid hormones are produced in insufficient amounts, and it is one of the most common animal models for studying its mechanisms and assessing therapeutic interventions