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Table 2: Potential Effects of GLP-1 in Arthritis GLP-1 receptor agonists show anti-inflammatory and cartilage-protective effects , though mechanisms are still under investigation

Ideal candidates for GLP-1 weight loss treatments are adults who struggle with obesity or have a BMI over 30, and those with weight-related medical conditions such as type 2 diabetes

Collectively, these preclinical studies illustrate that GLP-1RAs protect retinal neurons through a multi-pronged approach involving anti-inflammatory, anti-apoptotic, and anti-excitotoxic mechanisms

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Mounjaro was approved for use for type 2 diabetes in 2022

Austin PC, Stuart EA