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If trade-offs in evaluating APPH were made using an objective measure of health, such as discounted quality-adjusted life-years (QALYs), then the FDA would be designing regulations to dismantle barriers to adults accessing a wide range of flavored vaping and pouch products, all while continuing to account for the known risks of smoke-free nicotine use to youth

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Smoking-induced ED was corrected by the antioxidant vitamin C indicating an involvement of ROS such as superoxide in causing this phenomenon [1135] (Fig

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