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Considering the subtle membrane changes that are usually induced by smokeless tobacco due to its ability to generate free radicals which have been implicated with hepatic injuries and which when persistent may cause liver cirrhosis, at 4 weeks stage of the study, groups B, C and D showed cellular necrosis, inflammatory cell infiltration, hemorrhagic exudations, degenerative fatty changes with vacuolations, severe cellular infiltration with hemorrhage and distortions in parenchymal tissue architecture with hemorrhagic exudations Fig

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According to the Singapore Cancer Society1 and the World Health Organization (WHO)2, smoking is associated with at least 6 million deaths worldwide every year

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Hence, the objective of this study is to compare these two scales within two groups of smokers: those seeking help to quit in a smoking cessation clinic, and those from the general population

65 These cells are critical in maintaining the health of blood vessels and controlling blood flow and pressure