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Earlier studies identified Fusobacteria to be metabolically hyperactive in the oral community of OSCC patients (Yost et al., 2018), echoing the previous findings in colorectal cancer ( Prevotella species such as Prevotella intermedia and Prevotella nigrescens with oral inflammations like periodontitis has been reported ( Arecoline, a component of areca nut, has been shown to induce several pro-carcinogenic changes, including the production of nitrosamines and reactive oxygen species (Shiu and Chen, 2004) to induce changes in oral microbiome communities contributing to oral carcinogenesis (Yang et al., 2018)

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The Whole Health program is not experimental

Husky Chewing Tobacco is a popular brand of smokeless tobacco known for its strong and robust flavor, making it a favorite among tobacco enthusiasts who enjoy a bold and intense chewing experience

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doi:10.1136/tc.7.3.294
