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Additionally, due to the differences in puffing behaviour of dual users compared to solus smokers 29,30 , it is not clear if similar outcomes will be obtained in a population of solus smokers that are nave to e-cigarette use

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FDA Identified Root Causes of Attrition and Has Taken Some Steps to Address Them but Does Not Have Action Plans for All Causes ORA, which hires and manages investigators, led FDA efforts to identify the root causes of attrition