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Combining alcohol into the social smoking mix Not all adolescents smoke and drink alcohol, but these gateway drugs are often amongst the first experimental substances to be used concurrently

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Studies have drawn associations between periodontal disease and e-cigarette use, presenting with increased concentrations of localized inflammatory markers, an expansion in bone loss, increased levels of plaque, sulcular fluid volume increases, and deeper probing depths [132]

Aminoglycoside revival: review of a historically important class of antimicrobials undergoing rejuvenation

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Finally, the current findings need to be replicated in future studies to confirm their validity and generalizability