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Statistical comparisons were made using either Students t -test, one-way ANOVA, or two-way ANOVA as appropriate, followed by Bonferroni post hoc multiple comparisons test using GraphPad Prism version 8.0.0 for Windows (GraphPad Software, San Diego, CA)
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Stokholm J, Blaser MJ, Thorsen J, Rasmussen MA, Waage J, Vinding RK, Schoos AM, Kunoe A, Fink NR, Chawes BL, et al

Smoking can introduce new headaches by disturbing blood flow, oxygen delivery, and nerve stability in the brain, even in people without a past headache history

On July 1, Virginia will raise from 18 to 21 the legal age to purchase tobacco and nicotine products

E-cigarettes entered the US market around 2007 and, as of 2018, were used by about 3.2% of adults, down from 4% in 2014, according to the Centers for Disease Control and Prevention (CDC)
