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Grant Parks California State Auditor 621 Capitol Mall, Suite 1200 Sacramento, California 95814 Dear State Auditor Parks: Thank you for the opportunity to review and respond to the draft audit report on Proposition 56 tobacco tax

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Limitations First, analysis involved only the subgroup of smokers with hypertension, resulting in a smaller sample size (113 smokers) when compared to the 361 smokers randomized in GENTSMOKING

This report describes the diagnosis and treatment processes for two cases of etomidate-related hypokalemia in adult male patients with a recent history of smoking electronic cigarettes containing etomidate. The mechanisms of etomidate action were reviewed to better understand the development of etomidate-induced hypokalemia and adrenal insufficiency