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The people given the lower-nicotine cigarettes smoked 23% to 30% fewer cigarettes per day than those who smoked the cigarettes with 15.8 mg of nicotine per gram

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Biomarkers can be found in sputum, blood, and tissue samples

Beyond respiratory effects, evidence from human studies indicates that exposure to SHS is associated with a range of non-respiratory outcomes, including cardiovascular disease, urinary tract cancers, and immune dysregulation

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