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20-HETE, produced by CYP4A and CYP4F enzymes, is a potent vasoconstrictor that regulates renal and cerebral blood flow and is implicated in hypertension

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Mitochondrial dysfunction is a major contributing factor in the pathophysiology of glaucoma

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doi: 10.1158/1078-0432.CCR-06-1992 78 LouisDNPerryAWesselingPBratDJCreeIAFigarella-BrangerDet al

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