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Description
Although the epidemiological relationship between chronic arsenic exposure and the development of obesity has not been directly evaluated, an increase in the body mass index (BMI) is observed in individuals living in areas endemic with high concentrations of arsenic in water ( Evidence on animal models indicates that exposure to inorganic arsenic during adulthood or in utero affects body weight

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The endothelium is a monolayer of endothelial cells localized in the inner wall of blood and lymph vessels (131)

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The pathogenesis of AEP reportedly starts with antigenic stimulation of T-lymphocytes and, more specifically, Th2 lymphocytes (Nureki et al., 2005)
Among the included studies, 19 studies (24.76%) did not provide detailed information about participants characteristics, while the remaining studies reported various aspects such as age (51/71