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Over time, the long-term effects of nicotine on the brain lead to the development of tolerance, requiring higher doses to achieve the same pleasurable effect, thus driving addiction

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Article Text Abstract Objective The objectives of this scoping review are to examine existing research on the often-secretive contracts between tobacco manufacturers and retailers, to identify contract requirements and incentives, and to assess the impact of contracts on the sales and marketing of tobacco products in the retail setting

By Lee Hyo-sik KT&G has unveiled its heat-not-burn (HNB) e-cigarette, lil, which it hopes will establish its leadership in the rapidly growing alternative cigarette market