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Indeed, the estimated excess risk (ER) of 0.88 for use of ECIGs is only about 6.8% of the ER of 12.86 for smoking of cigarettes

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Additionally, smoking initiation tends to occur later

Compared with people who don't use, long-term, heavy marijuana smokers tend to have a smaller orbitofrontal cortex (OFC), a brain region critical for processing emotions and making decisions

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