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Fourth, as discussed previously, we did not include a nonbipolar disorder comparison group in the imaging study, making it difficult to assess the degree of mitochondrial dysfunction at baseline in our study cohort

Initially, trimethyllysine undergoes hydroxylation by trimethyllysine dioxygenase (TMLD), resulting in the formation of hydroxytrimethyllysine

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Mitochondrial superoxide contributes to hippocampal synaptic dysfunction and memory deficits in angelman syndrome model mice

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Antioxidant Defense: The tartrate portion of the drug acts as a powerful antioxidant