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Notch1 regulates endothelial apoptosis via the ERK pathway in chronic obstructive pulmonary disease

Participants were randomly assigned to groups before receiving the IMP

However, this period may be extended or shortened based on several conditions

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The mainstream smoke concentration of highly carcinogenic tobacco-specific nitrosamines (such as N-nitrosonornicotine, N-nitro-soanatabine, N-nitrosoanabasin, and nicotine-derived nitrosamine-ketone) was reduced 8- to 22-fold compared to conventional cigarettes [7, 59, 61, 85]
