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These results indicate a promoting effect of MSK1 on inflammation

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Trends Biochem

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Mice with TP53 mutation can develop the spontaneous liver inflammation, steatosis, and fibrosis, also found in HCC patients with a history of NAFLD 115,116

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What is cancer

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Thus, inactivated Akt results in increased apoptosis in testis

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Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development

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