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Furthermore, inhibition of the anti-autophagic mTORC1 can be enhanced by p53-mediated transactivation of tuberous sclerosis complex (TSC)2 that, together with TSC1, blocks mTORC1, enabling the autophagy process [80]
The products 8-oxoguanine (8-oxoG) and 8-oxo-2-deoxyguanosine (8-oxodG), guanine and deoxyguanosine oxidation products, respectively, are the biomarkers for UVA-induced oxidative DNA damage [27]
doi: 10.1016/j.bbcan.2020.188438
doi: 10.1101/cshperspect.a000109
Dimensions: Pendant is 1.5 inches long
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