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E-cigs may be an additional tool for reducing tobacco related harm when used to target smokers for whom current cessation programmes have had only limited success [61]

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The appeals court ruled that findings by the original Engle jury that all cigarettes are defective and that all cigarette makers were negligent in selling them cant be applied in individual suits

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Materials and Methods Preregistration The study protocol and analysis plan were preregistered on Open Science Framework ( and followed without amendment