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This function of nicotine-nAChR-angiogenesis was similar to the basic fibroblast growth factor (bFGF) [255]

Flue-cured bright tobacco blends were less alkaline and therefore easier to inhale than traditional varieties, notably those used in the pipe and cigar trade, where tobaccos were typically high in pH (circa 8) but generally too harsh to inhale

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The authors of the study caution that it took specific and "extreme" conditions to produce effects from the second hand high, and that their study design may not accurately reflect the real world: The size of room, amount of cannabis consumed, duration of exposure, and frequency of such exposure are all variables that likely would influence outcomes in the real world