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3 (September 2018): E7078
Genetic variants within alcohol metabolizing genes ( ALDH2 , ADH1B, and ADH4 ), genes related to neurotransmission such as GABRA2 (120122), and nicotinic and opioid receptor genes including CHRNA5 (120) and OPRM1 (123) show replicated associations to substance use disorders

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As a result, professional treatment is necessary to help adults safely and effectively recover from the most addictive drugs

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Cancer 55 , 3740 (1987)