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Nicotine is the substance in cigarettes that make them so addictive

For example, vaping among Minnesota 11th graders has dropped from 25% in 2019 to 8% in 2025

15, 16 Flavorings in e-cigarette liquids are also shown to be harmful when inhaled and can inflame and damage the airway and lung tissue

For adults who continue to use nicotine, smoke-free alternatives such as nicotine pouches may be one option

When a parent in an intervention practice reported smoking or having a household member who currently smoked tobacco, the parent received prescriptions for FDA-approved nicotine replacement therapy, such as nicotine patches or gum

Death counts from lung cancer were retrieved from the World Health Organization (WHO) Mortality Database [21]