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The subsequent ciliary states were highly enriched for mature ciliated cell genes, but the first of these in pseudotime was distinguished by basal body docking ( CEP290 and TTBK2 ) 48 and axoneme assembly ( IFT52 ) genes (Fig

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Lacking the stabilization of cholesterol, the side chain of W399 7.40 turned to another conformation (RT-III) at about 1200 ns, and RMSD PF and RMSD residues in CHL3 greatly increased at the same time (Supplementary Fig