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A crucial question was whether Philadelphias flavored tobacco law was whether in violation of the preemption clause, as the preemption clause pertains only to local laws that are related to existing state laws

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[22] Menthol Marketing to African Americans The tobacco industry also been marketing their menthol products to African Americans through targeted campaigns since the 1970s, concentrating advertising and promotions in predominately African American neighborhoods and with campaigns that exploit cultural hallmarks and stereotypes

Another study found that PM 2.5 caused upregulation of the expression of three target oncogenes, namely serpin family B member 2, solute carrier family 30, member 1, and aldo-keto reductase family 1 member C1, which are significantly expressed in human LUSC [217]

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