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Article Information Published Online: June 10, 2025

Packer M, Zile MR, Kramer CM, et al

[With] all four legs on the ground, you have a pretty stable base to lose weight, Primack says

For diabetes management, the target HbA1c is typically below 7% for most adults, though individualized targets may be appropriate based on age, comorbidities, and hypoglycemia risk

In T2DM, they are typically recommended as second-line or add-on therapymost often after metformin failureand more recently as first-line agents in people with established cardiovascular or renal disease [15, 16]

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.van Bloemendaal L, et al
