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Description
Dual-targeting approaches incorporating GLP-1R with co-receptors such as somatostatin receptor 2 (SSTR2), epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), or prostate-specific membrane antigen (PSMA) enhance target accessibility and therapeutic precision across heterogeneous lesions
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Timestamped Show Notes [00:00:00] Introduction - Brittany's home office with plants and dogs [02:02] The "holistic" medicine debate [04:02] Why Brittany opened Sweetgrass Psychiatry [07:00] Bringing family medicine in-house [10:01] The economics of integrating primary care [11:08] Scaling to 30 clinicians [13:41] Full suite of interventional services offered [15:08] Nine out of twenty patients on GLP-1s [16:15] Depression and metabolic syndrome: 50/50 overlap [19:03] GLP-1s and the mesolimbic system [20:24] JAMA Psychiatry study on semaglutide for alcohol use disorder [21:17] Dr

This provides novel insight into the remarkably different metabolic control mechanism and venom function in monotremes and an unique example of how different selective pressures act upon a single gene in the absence of gene duplication